Teratology society position statement on surveillance and prevalence estimation of neural tube defects

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Teratology Society Consensus Statement on use of folic acid to reduce the risk of birth defects.

Neural tube defects are common and severe birth defects that include the fatal condition anencephaly and the disabling condition spina bifida. Recent randomized controlled studies, (Crandall et al., ’95; Czeizel and Dudas, ’92; MRC Vitamin Study Research Group, ’91) have shown that women who consume folic acidcontaining supplements, while eating their usual diets, have 50–75% fewer infants with...

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Surveillance of neural tube defects in Israel.

BACKGROUND Open neural tube defects are among the most common malformations of the fetus. Secondary prevention by early diagnosis during pregnancy and abortion of affected fetuses result in a marked reduction of NTD incidence at birth. The dramatic effect of folic acid for primary prevention of these defects led to recommendations for folic acid supplementation in women of reproductive age. O...

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Spina bifida and anencephaly, the common form of neural tube defects, affect approximately 300 000 newborns each year worldwide. The effectiveness of folic acid supplementation in preventing their occurrence or recurrence has been unambiguous since 1991. In general, the prevalence of these abnormalities has decreased in the past 20 to 30 years because of periconceptional folate supplementation,...

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Neural tube defects surveillance: a national survey.

Neural tube defects (NTDs) are a class of birth defects characterized by defective closure of the neural tube during the first month of gestation. Reports from six states during the period of 1985-1994 demonstrated that the rate of NTDs in the United States varies by geographical area and by race/ethnicity. The reported rate ranged from 3.8 to 9.6 per 10,000 live births (CDC, ‘95). Recent epide...

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BACKGROUND In Canada, the first recommendations on the use of folic acid (FA) supplements by women planning a pregnancy or capable of becoming pregnant were issued in 1993. In 1998, fortification of flour with FA became mandatory. The objective of this study was to assess the impact of these measures on the prevalence of neural tube defects (NTDs) in the province of Quebec. METHODS The study ...

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ژورنال

عنوان ژورنال: Birth Defects Research

سال: 2018

ISSN: 2472-1727

DOI: 10.1002/bdr2.1434